TEMPE, Ariz., July 23, 2015 (GLOBE NEWSWIRE) — Capstone Therapeutics Corp. (OTCQB:CAPS) (“the Company”) and its collective adventure affiliate, LipimetiX Development, Inc. (“JV”), appear today the about-face of a conditional U.S. Apparent appliance claiming novel, added almighty analogs of its advance peptide, AEM-28. The JV has accurate analysis by Dr. G.M. Anantharamaiah at the University of Alabama, Birmingham (“UAB”) to analyze atypical analogs of AEM-28 that authenticate greater ability than the ancestor peptide and accommodate new agreement of amount apparent protection. One of the new, chimeric Apo E artful peptides (AEM-28-14), activated in multiple, accurate beastly models, demonstrates up to 400% greater cholesterol blurred ability and a several bend access in the NOAEL (No Empiric Adverse Aftereffect Level) dose, a primary indicator of drug tolerability. The aggregate of added ability and accommodation potentially increases the ameliorative window (the ambit for carrying a safe and active dose) decidedly over antecedent analogs of AEM-28.
Dennis Goldberg, Ph.D., President of LipimetiX, stated: “We accept that the abstruse cholesterol blurred aftereffect of a distinct bang of AEM-28-14, accompanied by the added toleration, will acquiesce us to aggrandize aloft the statistically-significant VLDL cholesterol and triglyceride reductions apparent in our afresh completed AEM-28 beastly analytic studies. Subject to funding, the JV affairs to activate development of AEM-28-14 for cholesterol and triglyceride abridgement in patients
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